| James Cagney | ...Richard 'Patsy' Gargan |
| Madge Evans | ...Dorothy Griffith |
| Arthur Byron | ...Judge H.J. Gilbert |
| Allen Jenkins | ...'Uncle' Mike |
| Dudley Digges | ...Mr. Thompson |
| Frankie Darro | ...James 'Jimmy' Smith |
| Sheila Terry | ...Blonde with Mike |
| Robert Barrat | ...Fred Smith, Jimmy's Father |
| Allen 'Farina' Hoskins | ...Joliet 'Smoke' Hemingway (as Farina) |
| Harold Huber | ...Joe, Gargan Henchman |
| Dorothy Peterson | ...Mrs. Smith, Jimmy's Mother |
| G. Pat Collins | ...Brandon, Head Guard (as George Pat Collins) |
| Edwin Maxwell | ...Louis Johnson |
| John Marston | ...Hopkins, Children Society's Lawyer |
| William V. Mong | ...Mr. Walter, the Auditor |
| Mickey Bennett | ...Butch Kilgore |
| Sidney Miller | ...Isadore 'Izzy' / 'Schnoz' Horowitz |
| Hobart Cavanaugh | ...Mr. Gorman, Tommy's Father |
| George Humbert | ...Mr. Carmonotti, Tony's Father |
| Raymond Borzage | ...Johnny 'Skinny' Stone |
| George Offerman Jr. | ...Charles 'Charlie' Burns |
| Charles E. Cane | ...Tommy 'Stupe' Gorman (as Charles Cane) |
| Beaudine Anderson | ...Boy (uncredited) |
| James Donlan | ...Sam, Political Boss (uncredited) |
| Sam Finn | ...Joe's Henchman (uncredited) |
| Ben Hendricks Jr. | ...Guard Taking Jimmy to Thompson (uncredited) |
| Gladden James | ...Car Owner Paying 25 Cents (uncredited) |
| Wilfred Lucas | ...Bill, a Guard (uncredited) |
| Larry McGrath | ...Johnston's Assistant (uncredited) |
| Jack McHugh | ...Boy Prosecutor (uncredited) |
| Bert Moorhouse | ...Joe's Henchman Playing Cards (uncredited) |
| Adrian Morris | ...Car Owner Who Won't Pay (uncredited) |
| Frank O'Connor | ...Policeman in Court (uncredited) |
| Henry Otho | ...Guard in School Armory (uncredited) |
| Bob Perry | ...Collector (uncredited) |
| Hector Sarno | ...Hollis, Injured Proprietor (uncredited) |
| Andy Shuford | ...Boy Judge (uncredited) |
| William H. Strauss | ...Mr. Horowitz, Izzy's father (uncredited) |
| Charles Sullivan | ...Collector (uncredited) |
| Ben Taggart | ...Sheriff (uncredited) |
| Fred 'Snowflake' Toones | ...Mr. Hemingway, Smoke's Father (uncredited) |
| Sailor Vincent | ...Guard (uncredited) |
| Huey White | ...Joe's Henchman (uncredited) |
| Charles C. Wilson | ...Wilson, the Kind Guard (uncredited) |
| Harry Wilson | ...Joe's Henchman (uncredited) |
| Dorothea Wolbert | ...Mrs. Burns, Charlie's Mother (uncredited) |
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